Endocrine Abstracts

Background: Bariatric surgery is known to dramatically increase insulin sensitivity in severely obese adults. However quantifying insulin sensitivity in these patients with methods such as the hyperinsulinaemic euglycaemic clamp is technically challenging. The leptin to adiponectin ratio (LAR) has previously been validated as a measure of whole body insulin sensitivity. Leptin is a known mediator of metabolic and cardiovascular complications of obesity. Adiponectin has anti-at...

BackgroundStructured lifestyle modification programmes are offered as first line treatment to patients referred to bariatric specialist services. We sought to describe changes in anthropometric and metabolic characteristics in a cohort of bariatric patients following completion of an eight-week, multidisciplinary group-based lifestyle intervention focussed on diet and physical activity.MethodsWe conducted a p...